Performance of selected nonparametric tests for discrete longitudinal data under different patterns of missing data.
J Biopharm Stat
; 19(1): 190-203, 2009.
Article
em En
| MEDLINE
| ID: mdl-19127475
ABSTRACT
Comparison of changes over time of a continuous response variable between treatment groups is often of main interest in clinical trials. When the distributional properties of the continuous response variable are not regular enough, or when the response is discrete, nonparametric techniques have been used. The relative performances of selected repeated measures nonparametric two-sample tests proposed by Wei and Lachin, Koziol, Wei and Johnson, and the adapted Wilcoxon Rank-Sum test are compared through simulations based on quality of life data. The Wilcoxon Rank-Sum test is the most powerful and is not significantly affected by the different patterns of missing data.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ensaios Clínicos Controlados Aleatórios como Assunto
/
Estatísticas não Paramétricas
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article