Side-effects of antipsychotic medication and health-related quality of life in schizophrenia.
Acta Psychiatr Scand Suppl
; (438): 22-8, 2009.
Article
em En
| MEDLINE
| ID: mdl-19132963
ABSTRACT
OBJECTIVE:
This analysis used data from the large (n = 1208) European Schizophrenia Cohort to examine the association between subjective side-effects of antipsychotic medication and the Mental and Physical Composite Scores (MCS; PCS) of the SF-36 scale.METHOD:
Relationships between the subjective evaluation of side-effects identified from the Subjective Side-Effects Scale and the adjusted mean score on the PCS and MCS were examined. Where appropriate, these associations of subjective side-effects were compared with those of the same side-effects measured objectively.RESULTS:
In this study, subjective side-effects of antipsychotic medication were linked either to both the PCS and the MCS or, in a few instances, to neither. Subjective evaluations of sexual side-effects were associated only with the MCS, those of sialorrhoea only with the PCS. Objective ratings of extrapyramidal side-effects were related neither to PCS nor to MCS.CONCLUSION:
These data suggest that side-effects, whether subjective or objective, may need to be considered individually in relation to their impact on quality of life.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
/
Esquizofrenia
/
Psicologia do Esquizofrênico
/
Antipsicóticos
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article