Incidence and treatment results of laryngopharyngeal reflux in chronic obstructive pulmonary disease.
Eur Arch Otorhinolaryngol
; 266(8): 1267-71, 2009 Aug.
Article
em En
| MEDLINE
| ID: mdl-19221778
ABSTRACT
Laryngopharyngeal reflux (LPR) is defined as the movement of gastric content towards the larynx and the pharynx and it may cause respiratory symptoms or difficulty in their control. We aimed to find the frequency of LPR in chronic obstructive pulmonary disease (COPD) patients and to investigate its effect on COPD symptoms and the results of its treatment. At baseline 30 (20 male, 10 female, mean age 65 +/- 10 years) COPD patients completed LPR and COPD symptom questionnaires and 13 (44%) were diagnosed with LPR based on laryngeal examination. Patients with LPR were given 2 months of PPI treatment, after which LPR and COPD symptom questionnaires, laryngeal examinations and pulmonary function tests were repeated. Following the treatment, significant improvements in COPD symptom index, LPR symptom index and laryngeal examination findings were observed in patients with LPR (P < 0.01, P < 0.01, P < 0.0001, respectively). Treatment of LPR resulted in a significant improvement in the symptoms of COPD.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Refluxo Gastroesofágico
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Doença Pulmonar Obstrutiva Crônica
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Inibidores da Bomba de Prótons
Tipo de estudo:
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article