Intravesical electromotive drug administration of mitomycin-C for non-muscle invasive bladder cancer.
Arch Ital Urol Androl
; 80(4): 157-61, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-19235432
ABSTRACT
This article reviews intravesical application of electromotive drug administration (EMDA) for the treatment of bladder cancer and the evidence in support of intravesical passive diffusion chemotherapy in the management of non-muscle invasive bladder cancer. Two recently published randomised trials adopting protocols that use EMDA to enhance urothelial transport of intravesical mitomycin-C showed it provided a therapeutical advantage and suggested that intravesical passive diffusion administration of chemotherapeutic drugs may be suboptimal. Further studies are required to demonstrate feasibility and advantage of intravesical EMDA of mitomycin-C in the wider uro-oncological community.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Bexiga Urinária
/
Mitomicina
/
Eletroquimioterapia
/
Antibióticos Antineoplásicos
Tipo de estudo:
Clinical_trials
/
Guideline
Limite:
Humans
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article