[Mapping of point mutations leading to loss of virus ECH011 affinity for receptor DAF (CD55)].
Vopr Virusol
; 54(1): 41-4, 2009.
Article
em Ru
| MEDLINE
| ID: mdl-19253731
ABSTRACT
Comparative sequence of the structural part of genomes pf the original daf+ clone and two derived daf- mutant clones (101 and 103) was analyzed to map mutations responsible for the loss of affinity for the receptor glycoprotein DAF (CD55). The obtained nucleotide sequences (EU167520, EU167521, EU167522) were deposited in the GenBank. There were single point mutations causing amino acid changes in VP2 protein S145 --> N in clone 101 and G162 --> E in clone 103.
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Base de dados:
MEDLINE
Assunto principal:
Genoma Viral
/
Mutação Puntual
/
Enterovirus Humano B
/
Antígenos CD55
Limite:
Animals
/
Humans
Idioma:
Ru
Ano de publicação:
2009
Tipo de documento:
Article