Unprecedented selectivity via electronic substrate recognition in the 1,4-addition to cyclic olefins using a chiral disulfoxide rhodium catalyst.
Angew Chem Int Ed Engl
; 48(15): 2768-71, 2009.
Article
em En
| MEDLINE
| ID: mdl-19260000
ABSTRACT
From zero to hero? Sulfoxides are generally not considered useful ligand entities in asymmetric metal catalysis. However, a chiral disulfoxide as a chelating ligand in the rhodium-catalyzed 1,4-addition of aryl boronic acids to cyclic, alpha,beta-unsaturated ketones and esters gives impressive catalytic results, thus opening the door to future applications of this new chiral ligand class.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ródio
/
Sulfóxidos
/
Cicloparafinas
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article