Active case finding of undetected tuberculosis among chronic coughers in a slum setting in Kampala, Uganda.
Int J Tuberc Lung Dis
; 13(4): 508-13, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-19335958
ABSTRACT
SETTING:
Kisenyi slum in peri-urban Kampala, Uganda.OBJECTIVES:
Using chronic cough (> or = 2 weeks) inquiry as a screening tool to identify undetected smear-positive tuberculosis (TB) cases and to describe the characteristics of smear-positive TB cases detected by active case finding.DESIGN:
A house-to-house survey was conducted in five randomly selected villages in Kampala between June and August 2005. A sample of households was visited; adults aged > or = 15 years were consecutively interviewed to identify those with chronic cough. Three sputum specimens were collected and examined by smear microscopy.RESULTS:
Among 930 individuals, we identified 189 (20%) chronic coughers. Of these, we found 33 (18%) undiagnosed smear-positive cases. The newly detected cases had an even sex distribution (P = 0.47), a median age of 30 years, a median cough duration of 1 month and 55% had acid-fast bacilli 1+ sputum smear grade.CONCLUSION:
These findings suggest that active case finding could supplement DOTS to yield additional smear-positive TB cases, lead to early diagnosis and thus shorten the duration of infectiousness before effective chemotherapy is initiated. In communities such as Kisenyi, this is a feasible strategy that may prove useful for TB control, but its cost-effectiveness needs to be evaluated. Early health care seeking for cough should be emphasized.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tuberculose
/
Áreas de Pobreza
/
Tosse
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
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Screening_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
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Middle aged
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article