Cerebral arteriolar thromboembolism in idiopathic hypereosinophilic syndrome.
Arch Neurol
; 66(4): 528-31, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-19364940
ABSTRACT
OBJECTIVE:
To describe imaging findings as well as postmortem brain and cardiac pathology in a patient with fulminant idiopathic hypereosinophilic syndrome.DESIGN:
Case report.SETTING:
University hospital. PATIENT A 48-year-old right-handed man with hypereosinophilia, rapidly progressive encephalopathy, and focal neurological deficits who died 22 days after presentation. MAIN OUTCOMEMEASURES:
Physical examination, radiologic, and neuropathologic examination results.RESULTS:
Imaging of the brain revealed bihemispheric ischemic changes in and beyond the watershed distributions. Pathology review demonstrated mural cardiac thrombus that likely caused cardioembolism as well as diffuse microangiopathy despite resolution of the hypereosinophilia.CONCLUSIONS:
Timely recognition of idiopathic hypereosinophilic syndrome may enable aggressive treatment prior to widespread cardioembolism and degranulation that result in devastating cerebrovascular complications.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Processamento de Imagem Assistida por Computador
/
Tomografia Computadorizada por Raios X
/
Síndrome Hipereosinofílica
/
Infarto da Artéria Cerebral Anterior
/
Imagem de Difusão por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article