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Fourier deconvolution reveals the role of the Lorentz function as the convolution kernel of narrow photon beams.
Djouguela, Armand; Harder, Dietrich; Kollhoff, Ralf; Foschepoth, Simon; Kunth, Wolfgang; Rühmann, Antje; Willborn, Kay; Poppe, Björn.
Afiliação
  • Djouguela A; Medical Radiation Physics Group, University of Oldenburg, Oldenburg, Germany.
Phys Med Biol ; 54(9): 2807-27, 2009 May 07.
Article em En | MEDLINE | ID: mdl-19369712
ABSTRACT
The two-dimensional lateral dose profiles D(x, y) of narrow photon beams, typically used for beamlet-based IMRT, stereotactic radiosurgery and tomotherapy, can be regarded as resulting from the convolution of a two-dimensional rectangular function R(x, y), which represents the photon fluence profile within the field borders, with a rotation-symmetric convolution kernel K(r). This kernel accounts not only for the lateral transport of secondary electrons and small-angle scattered photons in the absorber, but also for the 'geometrical spread' of each pencil beam due to the phase-space distribution of the photon source. The present investigation of the convolution kernel was based on an experimental study of the associated line-spread function K(x). Systematic cross-plane scans of rectangular and quadratic fields of variable side lengths were made by utilizing the linear current versus dose rate relationship and small energy dependence of the unshielded Si diode PTW 60012 as well as its narrow spatial resolution function. By application of the Fourier convolution theorem, it was observed that the values of the Fourier transform of K(x) could be closely fitted by an exponential function exp(-2pilambdanu(x)) of the spatial frequency nu(x). Thereby, the line-spread function K(x) was identified as the Lorentz function K(x) = (lambda/pi)[1/(x(2) + lambda(2))], a single-parameter, bell-shaped but non-Gaussian function with a narrow core, wide curve tail, full half-width 2lambda and convenient convolution properties. The variation of the 'kernel width parameter' lambda with the photon energy, field size and thickness of a water-equivalent absorber was systematically studied. The convolution of a rectangular fluence profile with K(x) in the local space results in a simple equation accurately reproducing the measured lateral dose profiles. The underlying 2D convolution kernel (point-spread function) was identified as K(r) = (lambda/2pi)[1/(r(2) + lambda(2))](3/2), fitting experimental results as well. These results are discussed in terms of their use for narrow-beam treatment planning.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fótons / Análise de Fourier Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fótons / Análise de Fourier Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2009 Tipo de documento: Article