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Significant increase in the apparent incidence of essential thrombocythemia related to new WHO diagnostic criteria: a population-based study.
Girodon, François; Bonicelli, Gilles; Schaeffer, Céline; Mounier, Morgane; Carillo, Serge; Lafon, Ingrid; Carli, Paule Marie; Janoray, Inès; Ferrant, Emmanuelle; Maynadié, Marc.
Afiliação
  • Girodon F; Laboratoire d'Hématologie, Hôpital du Bocage, CHU de Dijon, Dijon, France. francois.girodon@chu-dijon.fr
Haematologica ; 94(6): 865-9, 2009 Jun.
Article em En | MEDLINE | ID: mdl-19377078
To observe the effect of the new World Health Organization (WHO) criteria on the incidence of myeloproliferative neoplasms, we performed a retrospective study of a population-based registry in the Côte d'Or area, France, from 1980 to 2007. A total of 524 myeloproliferative neoplasms were registered for the 1980-2007 period, including 135 polycythemia vera, 308 essential thrombocythemia and 81 idiopathic myelofibroses. No change in the incidence of either polycythemia vera or idiopathic myelofibrosis was observed for the 2005-2007 period, compared to 1980-2004. On the contrary, a pronounced increase in the incidence of essential thrombocythemia was noted after 2005, mainly due to the use of JAK2 mutation screening and a lower threshold of platelet count. Our study confirms the relevance of the new WHO diagnostic criteria in allowing earlier diagnosis of essential thrombocythemia.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema de Registros / Trombocitemia Essencial / Transtornos Mieloproliferativos Tipo de estudo: Diagnostic_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: Europa Idioma: En Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema de Registros / Trombocitemia Essencial / Transtornos Mieloproliferativos Tipo de estudo: Diagnostic_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: Europa Idioma: En Ano de publicação: 2009 Tipo de documento: Article