[Antiphospholipid syndrome in the year 2009]. / Antifosfolipidový syndrom v roce 2009.

Antiphospholipid syndrome is a prothrombotic disorder characterized by vascular occlusions and/or pregnancy morbidity in the presence of antiphospholipid antibodies. These autoantibodies represent a large and heterogenous family of circulating immunoglobulins usually identified as anticardiolipin antibodies and antibodies directed against beta2-glykoprotein I or as lupus anticoagulant. A number of criteria for diagnosis of antiphospholipid syndrome have been proposed. In this review, we focused on long-term process of diagnostic procedures development and future directions in scientific research in this field.