Temporary mechanical circulatory support for severe cardiac failure: experimental study.
Int J Artif Organs
; 14(8): 466-72, 1991 Aug.
Article
em En
| MEDLINE
| ID: mdl-1937937
We describe a technique for mechanical cardiac assistance in an acute model of severe cardiac failure. Cardiac dysfunction was induced by a high dose of halothane in 13 dogs. Seven served as controls. Following median sternotomy, a pneumatically driven device was implanted in the other six dogs in a para-aortic position, using a simple surgical technique without cardiopulmonary bypass. The aorta was cross-clamped during cardiac assistance. During hemodynamic studies, the seven control animals with induced cardiac failure showed high end-diastolic left ventricular and right atrial pressures with low cardiac index and systolic left ventricular and aortic pressures. All dogs in this group died within 30 minutes. Use of a monovalvular cardiac assist device in the experimental group of six dogs to pump blood from the aortic root to the descending aorta in a counterpulsation manner, confirmed good preservation of systemic hemodynamic parameters after induction of heart failure. All animals in this treated group survived more than 45 minutes. Hemodynamically, the device acts as a new ventricle and the impaired left ventricle functionally becomes a left atrium. This condition is clinically appropriate for recovery of left ventricular function in severe acute myocardial failure.
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Base de dados:
MEDLINE
Assunto principal:
Contrapulsação
/
Coração Auxiliar
/
Insuficiência Cardíaca
/
Hemodinâmica
Limite:
Animals
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article