Metabolic labeling of sialic acids in living animals with alkynyl sugars.
Angew Chem Int Ed Engl
; 48(22): 4030-3, 2009.
Article
em En
| MEDLINE
| ID: mdl-19388017
ABSTRACT
Sialome sweet sialome As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living animals, enabling future identification of new biomarkers.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Siálicos
/
Azidas
/
Glicoproteínas
/
Hexosaminas
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article