Update on Campylobacter jejuni vaccine development for preventing human campylobacteriosis.
Expert Rev Vaccines
; 8(5): 625-45, 2009 May.
Article
em En
| MEDLINE
| ID: mdl-19397419
ABSTRACT
Campylobacteriosis constitutes a serious medical and socioeconomic problem worldwide. Rapidly increasing antibiotic resistance of bacterial strains compels us to develop alternative therapeutic strategies and to search for efficient immunoprophylactic methods. The vast majority of Campylobacter infections in developed countries occur as sporadic cases, mainly caused by eating undercooked Campylobacter-contaminated poultry. The most efficient strategy of decreasing the number of human Campylobacter infections is by implementing protective vaccinations for humans and/or chickens. Despite more than 10 years of research, an effective anti-Campylobacter vaccine has not been developed. This review highlights our increasing knowledge of Campylobacter interaction with host cells and focuses on recently published data describing the efficacy of anti-Campylobacter vaccine prototypes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Campylobacter
/
Vacinas Bacterianas
/
Campylobacter jejuni
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article