Impact of acute and chronic risk factors on use of evidence-based treatments in patients in Australia with acute coronary syndromes.
Heart
; 95(17): 1442-8, 2009 Sep.
Article
em En
| MEDLINE
| ID: mdl-19460772
ABSTRACT
OBJECTIVE:
To determine whether acute risk factors (ARF) and chronic risk factors (CRF) contribute differently to the use of evidence-based treatments (EBT) for patients with acute coronary syndromes (ACS).DESIGN:
Data were collected through a prospective audit of patients with ACS. Management was analysed by the presence of acute myocardial risk factors and chronic comorbid risk factors at presentation.SETTING:
39 hospitals across Australia. PATIENTS 2599 adults presenting with ACS.INTERVENTIONS:
None. MAIN OUTCOMEMEASURES:
Use of EBT, in-hospital and 12-month death, recurrent myocardial infarction and bleeding.RESULTS:
The number of ARF and CRF at presentation predicted in-hospital and 12-month death, recurrent myocardial infarction and bleeding. Patients with higher numbers of ARF were more likely to receive EBT (aspirin at presentation, 81.1% for zero ARF to 85.7% for > or =3 ARF, p<0.001; angiography 45.9% to 67.5%, p<0.001; reperfusion for ST elevation 50% to 70%, p = 0.392; beta blocker at discharge 66.5% to 74.4%, p<0.001). Patients with higher numbers of CRF were less likely to receive EBT (aspirin at presentation 90.4% for zero CRF to 68.8% for > or =4 CRF, p<0.001; angiography 78.8% to 24.7%, p<0.001; reperfusion for ST elevation 73.4% to 30%; p<0.001, beta blocker at discharge 75.2% to 55.6%; p<0.001). In multivariate regression analysis, ARF and CRF were the strongest predictors of receiving or failing to receive EBT, respectively.CONCLUSIONS:
Patients presenting with many ARF are more likely to receive EBT, while patients presenting with many CRF are less likely to receive them. This has important implications for future quality-improvement efforts.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Medicina Baseada em Evidências
/
Síndrome Coronariana Aguda
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
País como assunto:
Oceania
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article