Unrelated bone marrow transplant for congenital amegakaryocytic thrombocytopenia: report of two cases and review of the literature.
Pediatr Transplant
; 14(4): E42-5, 2010 Jun.
Article
em En
| MEDLINE
| ID: mdl-19490489
ABSTRACT
CAMT is a very rare cause of thrombocytopenia in infants. Most of the patients will progress to marrow failure. Allogeneic stem cell transplant remains the only curative therapy. We present two patients with CAMT who underwent an unrelated donor bone marrow transplant, one after developing marrow failure and another early in the course of the disease. Both patients tolerated the transplant with minimal toxicity and durable engraftment. We also present a comprehensive review of the literature for unrelated donor transplant for this condition.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Trombocitopenia
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Transplante de Medula Óssea
Limite:
Female
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Humans
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Infant
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article