Retrospective cohort study of 163 pediatric glaucoma patients.
Can J Ophthalmol
; 44(3): 323-7, 2009 Jun.
Article
em En
| MEDLINE
| ID: mdl-19491991
ABSTRACT
OBJECTIVE:
The aim of our study was to describe a cohort of pediatric glaucoma patients in Quebec.DESIGN:
This study was a retrospective medical record review.PARTICIPANTS:
The study included patients younger than 18 years who were diagnosed with glaucoma between 1980 and 2000 and monitored at the Ophthalmology Clinic of the Sainte-Justine University Hospital Centre (Centre Hospitalier Universitaire Sainte-Justine) and had ocular hypertension or glaucoma in at least 1 eye.METHODS:
The data gathered concerned patients' information, the surgical procedures performed post diagnosis associated with the glaucoma diagnosis, and the drugs prescribed.RESULTS:
The study included 163 patients (254 eyes), a total of 374 surgical procedures, and the use of 2885 antiglaucoma drug therapies. For the 4 most frequent pathologies, patients were monitored for 8.4 (SD 4.2) years for aphakic glaucoma/pseudophakic glaucoma, 10.0 (SD 5.5) years for congenital glaucoma, 9.0 (SD 5.2) years for Axenfeld-Rieger syndrome, and 7.5 (SD 3.4) years for uveitic glaucoma. In total, 113 patients had at least 1 surgical procedure (69.3%). Before 1985, only timolol, pilocarpine, epinephrine, acetazolamide, and dipivefrin were used. Other beta blockers then appeared (betaxolol, levobunolol between 1985 and 1990, and the timolol-pilocarpine association between 1990 and 1995). After 1995, we saw the arrival of a new class of prostaglandin F2 alpha analogues, with latanoprost and other carbonic acid anhydrase inhibitors such as dorzolamide and brinzolamide.CONCLUSIONS:
This study illustrates the great variety of glaucoma diagnostic subgroups and the use of surgery and drug therapies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Glaucoma
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Cirurgia Filtrante
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Anti-Hipertensivos
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article