Synthesis of chiral fluorine-tagged reference standards for the (19)F NMR-based stereochemical analysis of sulfoxides at trace analytical levels.

Tremblay, Amy E; Lao, Kim Y Y; Hodgson, Derek J; Dawson, Brian; Buist, Peter H

Tremblay, Amy E; Lao, Kim Y Y; Hodgson, Derek J; Dawson, Brian; Buist, Peter H.

Afiliação

Tremblay AE; Ottawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, Canada.

Bioorg Med Chem Lett ; 19(17): 5146-50, 2009 Sep 01.

Article em En | MEDLINE | ID: mdl-19632835

ABSTRACT

ABSTRACT

Chiral fluorine-tagged sulfoxides of known absolute configuration have been synthesized. These compounds are required as reference standards to validate a (19)F NMR-based micromethod for the stereochemical analysis of biosynthetic fatty acyl sulfoxides.

Assuntos

Flúor/química; Espectroscopia de Ressonância Magnética/métodos; Sulfóxidos/química; Espectroscopia de Ressonância Magnética/normas; Padrões de Referência; Estereoisomerismo; Sulfóxidos/síntese química

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfóxidos / Espectroscopia de Ressonância Magnética / Flúor Idioma: En Ano de publicação: 2009 Tipo de documento: Article

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