[Carotid artery disease and human immunodeficiency virus (HIV) infection]. / Enfermedad vascular carotídea e infección por virus de inmunodeficiencia humana.
Neurologia
; 24(5): 318-30, 2009 Jun.
Article
em Es
| MEDLINE
| ID: mdl-19642035
ABSTRACT
INTRODUCTION:
Human immunodeficiency virus (HIV) infection provides patients an increased vascular risk, related to traditional vascular risk factors and metabolic and vascular disease induced by antiretroviral treatment and HIV infection itself.METHODS:
By reviewing current literature, this article analyses meaning and measurement of subclinical atherosclerosis in general population; factors inducing vascular risk in HIV infected patients; and published evidence about subclinical atherosclerosis in this population.RESULTS:
Carotid ultrasound measurement of carotid intimamedia thickness and atherosclerotic plaques, as surrogate markers of vascular risk, allows non-invasive quantification of subclinical atherosclerosis and it predicts vascular risk, of acute myocardial infarction or stroke. Studies in HIV-infected patients show different results, due to methodological heterogeneity that difficults comparisons. Most studies found a higher degree and progression of subclinical carotid atherosclerosis in HIV positive patients, compared to non-infected HIV controls, and it is associated to classical vascular risk factors, antiretroviral treatment and HIV infection itself.CONCLUSION:
Carotid ultrasound in HIV patients could stratify vascular risk in these patients and it represents an efficacious tool in atherosclerosis study.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Doenças das Artérias Carótidas
/
Infecções por HIV
/
HIV
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
Es
Ano de publicação:
2009
Tipo de documento:
Article