COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia.
Psychiatry Res
; 169(2): 173-5, 2009 Sep 30.
Article
em En
| MEDLINE
| ID: mdl-19647329
ABSTRACT
The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in 110 schizophrenia patients and 96 controls. Patients had lower steady-state pursuit gain and made more frequent saccades than controls. Genotype was not associated with schizophrenia or SPEM, in either group or the combined sample. SPEM deficits in schizophrenia appear to be determined by genotypes other than rs4680, although the study may have lacked power to detect small effects.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Acompanhamento Ocular Uniforme
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Valina
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Catecol O-Metiltransferase
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Transtornos da Motilidade Ocular
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Predisposição Genética para Doença
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Polimorfismo de Nucleotídeo Único
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Metionina
Tipo de estudo:
Etiology_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article