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Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease.
Marinho, Cláudio R F; Nuñez-Apaza, Luis N; Bortoluci, Karina R; Bombeiro, André L; Bucci, Daniella Z; Grisotto, Marcos G; Sardinha, Luiz R; Jorquera, Christian E; Lira, Sergio; Lima, Maria Regina D'Império; Alvarez, José M.
Afiliação
  • Marinho CR; Department of Immunology, Biomedical Sciences Institute, University of São Paulo, Av. Professor Lineu Prestes, 1730, São Paulo, SP, CEP-05508-000, Brazil.
Microbes Infect ; 11(13): 1037-45, 2009 Nov.
Article em En | MEDLINE | ID: mdl-19660570
ABSTRACT
The physiopathology of Chagas' disease has been largely defined in murine infections with virulent strains which partially represent parasite diversity. This report reviews our studies with Sylvio X10/4 parasites, a Trypanosoma cruzi clone that induces no acute phase but in C3H/He mice leads to chronic myocarditis resembling the human disease.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trypanosoma cruzi / Doença de Chagas Limite: Animals Idioma: En Ano de publicação: 2009 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trypanosoma cruzi / Doença de Chagas Limite: Animals Idioma: En Ano de publicação: 2009 Tipo de documento: Article