Endoplasmic reticulum (ER) stress-suppressive compounds from scrap cultivation beds of the mushroom Hericium erinaceum.
Biosci Biotechnol Biochem
; 73(8): 1908-10, 2009 Aug.
Article
em En
| MEDLINE
| ID: mdl-19661683
ABSTRACT
Four compounds were isolated from scrap cultivation beds of the mushroom, Hericium erinaceum. Compounds 1-4 were identified as methyl 4-hydroxy-3-(3-methylbutanoyl) benzoate, 2-chloro-1,3-dimethoxy-5-methylbenzene, methyl 4-chloro-3,5-dimethoxybenzoate, and 4-chloro-3,5-dimethoxybenzaldehyde by an interpretation of the NMR and MS data, respectively. This is the first reported isolation of 1 from a natural source. All the compounds showed protective activity against endoplasmic reticulum stress-dependent cell death.
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Base de dados:
MEDLINE
Assunto principal:
Estresse Fisiológico
/
Basidiomycota
/
Retículo Endoplasmático
Limite:
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article