[Clinical observation of heparin-induced thrombocytopenia].
Zhonghua Yi Xue Za Zhi
; 89(20): 1405-7, 2009 May 26.
Article
em Zh
| MEDLINE
| ID: mdl-19671335
ABSTRACT
OBJECTIVE:
To explore the treatment of heparin-induced thrombocytopenia (HIT) in venous thromboembolism.METHODS:
A total of 202 patients with venous thromboembolism without anticoagulation contraindications were enrolled. All of them were treated with low molecular weight heparin (LMWH) and/or unfractionated heparin (UFH). The peripheral blood cells were examined regularly.RESULTS:
HIT occurred in 6 patients. And argatroban was used to treat HIT. The overall incidence rate of HIT in this study was 2.97%. The time of occurrence of HIT was about Days 3 - 9 after using heparin. The platelet recovered to the basic level at Days 3 - 7 after withdrawing heparin and initiating argatroban.CONCLUSION:
The count of platelet should be measured in the patients receiving regular LMWH and/or UFH therapy. And the above regimen should be discontinued timely when the platelet count declined progressively by over 50%. Argatroban was effective.
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Base de dados:
MEDLINE
Assunto principal:
Trombocitopenia
/
Heparina
/
Anticoagulantes
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Ano de publicação:
2009
Tipo de documento:
Article