A focal lesion in the falx cerebri: Harbinger of classic stage 4 neuroblastoma in an infant cured despite residual disease after minimal therapy.
Pediatr Blood Cancer
; 53(7): 1340-2, 2009 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-19711437
ABSTRACT
An asymptomatic 11-week-old male received no treatment after he was classified as having a suspected atypical form of MYCN-nonamplified hyperdiploid stage 4S neuroblastoma (NB), with masses in an adrenal gland, subcutaneous tissues, and the falx cerebri. Within 2 months, however, disease progressed in dura and bone marrow. Two cycles of low-dose chemotherapy achieved a partial response; treatment was discontinued. Complete remission was documented 24 weeks post-cycle 2, and has continued >6 years. The falx cerebri probably does not represent an atypical site for stage 4S NB, but stage 4 NB with favorable biology is sometimes curable with minimal therapy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
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Neoplasias das Glândulas Suprarrenais
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Dura-Máter
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Neoplasias Meníngeas
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Neuroblastoma
Limite:
Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article