Effect of a point-of-use water treatment and safe water storage intervention on diarrhea in infants of HIV-infected mothers.
J Infect Dis
; 200(8): 1186-93, 2009 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-19758095
ABSTRACT
To reduce mother-to-child transmission of human immunodeficiency virus (HIV) in resource-poor settings, the World Health Organization recommends exclusive breast-feeding for 6 months, followed by rapid weaning if replacement feeding is affordable, feasible, available, safe, and sustainable. In the Kisumu Breastfeeding Study (trial registration Clinicaltrials.gov identifier NCT00146380), infants of HIV-infected mothers who received antiretroviral therapy experienced high rates of diarrhea at weaning. To address this problem, mothers in the Kisumu Breastfeeding Study were given safe water storage vessels, hygiene education, and bleach for household water treatment. We compared the incidence of diarrhea in infants enrolled before (cohort A) and after (cohort B) implementation of the intervention. Cohort B infants experienced less diarrhea than cohort A infants, before and after weaning (P < .001 and P = .047, respectively); however, during the weaning period, there were no differences in the frequency of diarrhea between cohorts (P = 0.89). Testing of stored water in cohort B homes indicated high adherence (monthly range, 80%-95%) to recommended chlorination practices. Among infants who were weaned early, provision of safe water may be insufficient to prevent weaning-associated diarrhea.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Purificação da Água
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Transmissão Vertical de Doenças Infecciosas
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Diarreia
Limite:
Adolescent
/
Adult
/
Humans
/
Infant
/
Newborn
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article