New restriction fragment length polymorphism (probe E9) reveals the highest linkage disequilibrium in Italian CF patients.
Acta Univ Carol Med (Praha)
; 36(1-4): 102-4, 1990.
Article
em En
| MEDLINE
| ID: mdl-1983379
ABSTRACT
We report that the allele distribution for RFLP's flanking the CF gene differs between patients with and without pancreatic insufficiency. The present study confirms this difference. In both classes the linkage disequilibrium (LD) is highest with the RFLP revealed by probe E9. The haplotype distribution identified by these RFLP's can be used for indirect carrier detection.
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Base de dados:
MEDLINE
Assunto principal:
Fibrose Cística
Limite:
Humans
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article