Progesterone sperm chemoattraction may be modulated by its corticosteroid-binding globulin carrier protein.
Fertil Steril
; 93(7): 2450-2, 2010 May 01.
Article
em En
| MEDLINE
| ID: mdl-19896663
ABSTRACT
Progesterone, the main steroidal component secreted by the cumulus cells that surround the egg, chemotactically guides human spermatozoa. The aim of this work was to evaluate whether the carrier protein corticosteroid-binding globulin also participates in the sperm P chemotactic response. By means of videomicroscopy and image analysis, we observed that corticosteroid-binding globulin modulates the chemotactic activity of P, when a solution of corticosteroid-binding globulin + P is at the nanomolar range.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Progesterona
/
Espermatozoides
/
Transcortina
/
Quimiotaxia
Tipo de estudo:
Evaluation_studies
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article