[Preanalytical guidelines for clinical proteomics investigation of biological fluids]. / Recommandations préanalytiques pour les analyses de protéomique clinique des fluides biologiques.
Ann Biol Clin (Paris)
; 67(6): 629-39, 2009.
Article
em Fr
| MEDLINE
| ID: mdl-19939766
ABSTRACT
Research of new diagnosis or prognosis biomarkers is a major challenge for the management of patients with complex pathologies like cancer. Clinical proteomics is one of the recent approaches to identify these biomarkers in biological fluids. Over the last five years, many problems related to the variability and the quality control of these analyses have been observed. This was notably related to the different preanalytical status of each sample. A strong need for standardization of the critical preanalytical phases (collection, transport, processing, storage...) has been therefore recognized. With this goal in mind, working groups of the "Institut national du cancer" (INCa) and the "Société française de biologie clinique" (SFBC) proposed here preanalytical proteomics guidelines for the most common biological fluids plasma, serum, urine and cerebrospinal fluid. To goal is to provide the basis for the harmonization of the procedures in clinical laboratories and biobanks to allow an optimal use of biological collections.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Líquidos Corporais
/
Guias de Prática Clínica como Assunto
/
Técnicas de Laboratório Clínico
/
Técnicas e Procedimentos Diagnósticos
/
Proteômica
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limite:
Humans
Idioma:
Fr
Ano de publicação:
2009
Tipo de documento:
Article