Occupational immediate-type asthma and rhinitis due to rhodium salts.
Am J Ind Med
; 53(1): 42-6, 2010 Jan.
Article
em En
| MEDLINE
| ID: mdl-19953567
ABSTRACT
BACKGROUND:
Whereas platinum salts are well known occupational allergens, rhodium salts have not been identified as inhalative sensitizing substances.METHODS:
A 27-year-old atopic operator of an electroplating plant developed work-related shortness of breath and runny nose with sneezing after exposure to rhodium salts. Quantitative skin prick tests (SPT) and bronchial challenge tests with a dosimeter protocol were performed with quadrupling doses of the sodium chloride salts of rhodium (Na(3)RhCl(6)) and platinum (Na(2)PtCl(6)).RESULTS:
The patient showed positive SPT reactions and positive bronchial immediate-type reactions with rhodium and platinum salts. Sensitivity to rhodium salt was much higher than to platinum salt; the molar concentrations differed by a factor of 256 in SPT and a factor of 16 in bronchial challenges.CONCLUSIONS:
Rhodium salts should be considered as occupational immediate-type allergens.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Ródio
/
Rinite Alérgica Perene
/
Exposição Ocupacional
/
Galvanoplastia
/
Hipersensibilidade Imediata
/
Doenças Profissionais
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article