Steroidal saponins from Chlorophytum orchidastrum.
J Nat Prod
; 73(1): 7-11, 2010 Jan.
Article
em En
| MEDLINE
| ID: mdl-20028106
ABSTRACT
Six new spirostane-type saponins (1-6), named orchidastrosides A-F, and chloromaloside D were isolated from an ethanol extract of the roots of Chlorophytum orchidastrum. The saponins have neotigogenin or neogitogenin as the aglycon and oligosaccharidic chains possessing seven to nine sugar units. Their structures were elucidated mainly by 2D NMR spectroscopic analyses (COSY, TOCSY, NOESY, HSQC, and HMBC) and FABMS and HRESIMS. Compounds 1-6 were tested for cytotoxicity against two human colon cancer cell lines, HCT 116 and HT-29.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Saponinas
/
Espirostanos
/
Liliaceae
/
Antineoplásicos Fitogênicos
Limite:
Humans
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article