Comparison of Recombinant Proteins from Schistosoma japonicum for Schistosomiasis Diagnosis.
Clin Vaccine Immunol
; 17(3): 476-80, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-20053872
ABSTRACT
The most important animal reservoirs of Schistosoma japonicum in China are bovines. Diagnosis and control of bovine schistosomiasis is critical for reducing the prevalence of the disease. We screened defined diagnostic antigens that have the potential to increase the sensitivity and specificity of serological assays and to distinguish between active and prior infections. Five recombinant proteins with the potential to be diagnostic antigens were compared to the native soluble egg antigen preparation by enzyme-linked immunosorbent assay (ELISA). We evaluated the potentials of the recombinant proteins for discriminating active from prior infections, as well as the therapeutic efficacy of the established ELISA technique.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Esquistossomose Japônica
/
Ensaio de Imunoadsorção Enzimática
/
Antígenos de Helmintos
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article