Biodistribution of phenylboric acid derivative entrapped lipiodol and 4-borono-2-18F-fluoro-L-phenylalanine-fructose in GP7TB liver tumor bearing rats for BNCT.
Appl Radiat Isot
; 68(3): 422-6, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-20056428
ABSTRACT
A new phenylboric acid derivative entrapped lipiodol (PBAD-lipiodol) was developed as a boron carrier for the boron neutron capture therapy (BNCT) of hepatoma in Taiwan. The biodistribution of both PBAD-lipiodol and BPA-fructose was assayed in GP7TB hepatoma-bearing rat model. The highest uptake of PBAD-lipiodol was found at 2h post injection. The application of BNCT for the hepatoma treatment in tumor-bearing rats is suggested to be 2-4h post PBAD-lipiodol injection.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenilalanina
/
Ácidos Borônicos
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Radioisótopos de Flúor
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Terapia por Captura de Nêutron de Boro
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Óleo Iodado
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Neoplasias Hepáticas Experimentais
Limite:
Animals
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article