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Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases.
Kastrinsky, David B; Barry, Clifton E.
Afiliação
  • Kastrinsky DB; The National Institutes of Health, National Institute of Allergy and Infectous Diseases, Tuberculosis Research Section, Bethesda MD 20892.
Tetrahedron Lett ; 51(1): 197-200, 2010.
Article em En | MEDLINE | ID: mdl-20161438
ABSTRACT
A concise synthesis of (14)C labeled meropenem prepared from (14)C dimethylamine hydrochloride is described. Using a similar reaction sequence, the meropenem nucleus was also attached to biotin providing a probe for protein interaction studies.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2010 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2010 Tipo de documento: Article