Evaluation of the memory CD4+ and CD8+ T cells homeostasis during chronic venous disease of lower limbs.
Folia Histochem Cytobiol
; 47(3): 471-7, 2009 Jan.
Article
em En
| MEDLINE
| ID: mdl-20164034
ABSTRACT
More and more is known about the role of venous wall abnormalities and valvular incompetence in the development of chronic venous disorders (CVD). Unfortunately detailed mechanisms of CVD pathophysiology are not well understood. Recent studies focus on involvement of the inflammatory process in the structural remodeling of venous valves and venous wall. The aim of this study is to investigate and to document the memory T cells homeostasis in CVD patients. In this study we present lymphocytic changes in blood from varicose veins in terms of total CD4+ and CD8+ T cells and their particular subsets of memory T cells TN, TCM and TEM. Results suggest that immunological memory may be involved in the CVD development.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Vasculares
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Linfócitos T CD4-Positivos
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Linfócitos T CD8-Positivos
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Extremidade Inferior
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Homeostase
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Memória Imunológica
Tipo de estudo:
Evaluation_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article