StIKKing together: do multiple IKK pathways cooperate in the DNA-damage response?
Mol Cell
; 37(4): 453-4, 2010 Feb 26.
Article
em En
| MEDLINE
| ID: mdl-20188663
ABSTRACT
Although IKK-related kinases are known to augment immune pathways, their importance to DNA-damage response has not been previously elucidated; in this issue of Molecular Cell, Renner et al. (2010) show that genotoxic stress requires SUMOylated IKKvarepsilon to regulate NF-kappaB transcription and cell survival.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dano ao DNA
/
Transdução de Sinais
/
Apoptose
/
Quinase I-kappa B
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article