Electrically evoked nociceptive potentials for early detection of diabetic small-fiber neuropathy.
Eur J Neurol
; 17(6): 834-41, 2010 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-20192984
ABSTRACT
BACKGROUND AND PURPOSE:
This study investigated the utility of pain-related evoked potentials (PREP's) elicited by a nociceptive electrical stimulation of the skin (= electrically evoked nociceptive potentials) in early detection of diabetic small-fiber neuropathy.METHODS:
We studied 36 'young' (19-35 years) and 24 'older' (36-65 years) healthy subjects as well as 35 patients (35-64 years) with diabetes and neuropathic symptoms and 22 patients (34-64 years) with diabetes without neuropathic symptoms. Only patients with normal standard nerve conduction testing were included.RESULTS:
In patients with neuropathic symptoms, we found a significant increase in PREP latencies and decrease of amplitudes elicited from both, upper and lower limbs. In non-symptomatic diabetic patients, we observed PREP abnormalities from lower limbs only.CONCLUSIONS:
These data suggest that the method of pain-related evoked potentials elicited by a nociceptive electrical stimulation of the skin may contribute to the early detection of diabetic sensory neuropathy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dor
/
Neuropatias Diabéticas
/
Eletrofisiologia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Screening_studies
Limite:
Adult
/
Aged
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Female
/
Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article