Does registration of serial MRI improve diagnosis of dementia?
Neuroradiology
; 52(11): 987-95, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-20195590
ABSTRACT
INTRODUCTION:
We aimed to assess the value of a second MR scan in the radiological diagnosis of dementia.METHODS:
One hundred twenty subjects with clinical follow-up of at least 1 year with two scans were selected from a cognitive disorders clinic. Scans were reviewed as a single first scan (method A), two unregistered scans presented side-by-side (method B) and a registered pair (method C). Scans were presented to two neuroradiologists and a clinician together with approximate scan interval (if applicable) and age. Raters decided on a main and subtype diagnosis.RESULTS:
There was no evidence that differences between methods (expressed as relative odds of a correct response) differed between reviewers (p = 0.17 for degenerative condition or not, p = 0.5 for main diagnosis, p = 0.16 for subtype). Accordingly, results were pooled over reviewers. For distinguishing normal/non-progressors from degenerative conditions, the proportions correctly diagnosed were higher with methods B and C than with A (p = 0.001, both tests). The difference between method B and C was not statistically significant (p = 0.18). For main diagnosis, the proportion of correct diagnoses were highest with method C for all three reviewers; however, this was not statistically significant comparing with method A (p = 0.23) or with method B (p = 0.16). For subtype diagnosis, there was some evidence that method C was better than method A (p = 0.01) and B (p = 0.048).CONCLUSIONS:
Serial MRI and registration may improve visual diagnosis in dementia.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Reconhecimento Automatizado de Padrão
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Imageamento por Ressonância Magnética
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Aumento da Imagem
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Técnica de Subtração
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Demência
Tipo de estudo:
Diagnostic_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article