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Effects of electromagnetic pulse on bone metabolism of mice in vivo.
Li, Kang-Chu; Ma, Shi-Rong; Ding, Gui-Rong; Guo, Yao; Guo, Guo-Zhen.
Afiliação
  • Li KC; Department of Radiation Medicine, Fourth Military Medical University, Xi 'an 710032, Shaanxi China. kangchu@fmmu.edu.cn
Biomed Environ Sci ; 22(6): 518-21, 2009 Dec.
Article em En | MEDLINE | ID: mdl-20337226
OBJECTIVE: To study the effects of electromagnetic pulse (EMP) on bone metabolism of mice in vivo. METHODS: Twenty-four male BALB/c mice were divided into a control group and 2 experimental groups (n=8). The whole-body of mice in experimental groups were exposed to 50 kV/m and 400kV/m EMP, 400 pulses daily for 7 consecutive days at 2 seconds intervals. Alkaline phosphotase (ALP) activity, serum calcium concentration and osteocalcin level and trabecular bone volume (BV/TV, %) were measured immediately after EMP exposure by biochemical, ELISA and morphological methods. RESULTS: The ALP activity, serum calcium concentration and osteocalcin level and BV/TV in experimental groups remained unchanged after EMP exposure. Conclusion Under our experimental conditions, EMP exposure cannot affect bone metabolism of mice in vivo.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osso e Ossos / Campos Eletromagnéticos Limite: Animals Idioma: En Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osso e Ossos / Campos Eletromagnéticos Limite: Animals Idioma: En Ano de publicação: 2009 Tipo de documento: Article