Peptide and protein thioester synthesis via N-->S acyl transfer.
Org Biomol Chem
; 8(9): 1993-2002, 2010 May 07.
Article
em En
| MEDLINE
| ID: mdl-20401371
ABSTRACT
Peptide and protein thioesters are playing an increasingly prominent role in the chemical toolbox for protein assembly and modification through Native Chemical Ligation (NCL). In this Emerging Area we highlight recent developments in a somewhat surprising route to thioesters selective disruption of amides, the more stable carboxylic acid derivatives.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Compostos de Sulfidrila
/
Proteínas
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article