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Genetic polymorphisms of 15 STR loci in the population of the island of Cres (Croatia).
Novokmet, Natalija; Marjanovic, Damir; Skaro, Vedrana; Projic, Petar; Lauc, Gordan; Grahovac, Blazenka; Ostojic, Sasa; Kapovic, Miljenko; Rudan, Pavao.
Afiliação
  • Novokmet N; Institute for Anthropological Research, Gajeva 32, Zagreb, Croatia. natalija.novokmet@inantro.hr
Ann Hum Biol ; 38(1): 12-21, 2011 Jan.
Article em En | MEDLINE | ID: mdl-20446818
BACKGROUND: The population of the island of Cres presents one of the few persisting Eastern Adriatic isolates and is thereby suitable for human population differentiation analyses. AIM: The aim of this study was to analyse the genetic structure of the island of Cres with respect to its eight sub-populations and to compare the genetic variation of the island of Cres with other Eastern Adriatic islands and the Croatian mainland. SUBJECTS AND METHODS: Fifteen AmpFlSTR identifiler loci were analysed in a sample group of 122 unrelated autochthonous individuals from the island of Cres, Croatia. RESULTS: Analysis of STR polymorphisms revealed genetic homogeneity among sub-populations of the island of Cres and small but significant levels of genetic heterogeneity among geographically distant Eastern Adriatic islands. CONCLUSION: Despite a considerable degree of genetic homogeneity among the studied Eastern Adriatic islands, small but significant differentiation between distant islands indicates geographic sub-structuring which follows the isolation by distance model. This study is supportive of the notion that STR markers are useful for genetic differentiation between larger and geographically more distant regions.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Repetições de Microssatélites Tipo de estudo: Prognostic_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Repetições de Microssatélites Tipo de estudo: Prognostic_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2011 Tipo de documento: Article