Switching of inferred tropism caused by HIV during interruption of antiretroviral therapy.
J Clin Microbiol
; 48(7): 2586-8, 2010 Jul.
Article
em En
| MEDLINE
| ID: mdl-20484604
ABSTRACT
After interruption of highly active antiretroviral therapy, 15 out of 53 patients with the X4 HIV strain had a significantly larger decrease in CD4(+) T cell count (P = 0.001) and shorter length of treatment interruption (P = 0.02) than patients with the R5 strain. At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
HIV
/
Terapia Antirretroviral de Alta Atividade
/
Tropismo Viral
Limite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article