[Immunity in human schistosomiasis: hope for a vaccine]. / L'immunité dans les schistosomoses humaines: perspectives vaccinales.
Med Trop (Mars)
; 70(2): 189-97, 2010 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-20486361
ABSTRACT
Schistosomiasis remains a major worldwide public health problem in several endemic areas despite implementation of control measures. Vaccination would be an effective, long-term treatment option for future control of schistosomiasis. Although several parasite antigens have been identified as schistosomiasis vaccine candidates, major hurdles must still be overcome to develop a vaccine suitable for clinical trials in the field. Better understanding of immune responses to Schistosoma infection in both animal models and humans suggests that development of a vaccine is possible. The purpose of this review is to summarize the mechanisms of protective immunity against Schistosoma infection and to provide perspective on the development of a vaccine.
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Base de dados:
MEDLINE
Assunto principal:
Esquistossomose
/
Vacinas Protozoárias
Limite:
Animals
/
Humans
Idioma:
Fr
Ano de publicação:
2010
Tipo de documento:
Article