MRI changes associated with vigabatrin treatment mimicking tumor progression.
Pediatr Blood Cancer
; 55(6): 1221-3, 2010 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-20533524
ABSTRACT
Vigabatrin has been used as first-line treatment of infantile spasms. Reversible cerebral MRI signal changes have been reported to be associated with vigabatrin treatments. We report a case of a 5-month-old female who, following resection of an anaplastic oligodendroglioma developed, while treated with vigabatrin for seizures, abnormal DWI and FLAIR MRI signal changes worrisome for tumor progression or recurrence. Discontinuation of vigabatrin led to reversal of the MRI changes. This report highlights the fact that vigabatrin treatment can mimic tumor progression on MRI and confound management of tumors associated with seizures in pediatric patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oligodendroglioma
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Convulsões
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Neoplasias Encefálicas
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Vigabatrina
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Anticonvulsivantes
Tipo de estudo:
Etiology_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Infant
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article