[Quantiferon-TB Gold In-Tube test in the diagnosis of pulmonary and extra-pulmonary tuberculosis]. / Valor de QuantiFERON-TB Gold Test in Tube en el diagnóstico de tuberculosis pulmonar y extrapulmonar.
Enferm Infecc Microbiol Clin
; 28(10): 685-9, 2010 Dec.
Article
em Es
| MEDLINE
| ID: mdl-20570416
ABSTRACT
INTRODUCTION:
The Interferon-γ in vitro detection tests could be a useful tool in the diagnosis of active tuberculosis compared to Mycobacterium tuberculosis (MTB).METHODS:
The QuantiFERON-TB-Gold in Tube (QFG-IT) test was performed on the blood of 118 patients with active tuberculosis and the results compared with the tuberculin test.RESULTS:
The QFG-IT test was positive in 94 cases (79.7%), negative in 17 (14.4%) and indeterminate in 7 (5.9%). A negative or indeterminate QFG-IT test was more common in older patients (P=0.017) and in cases with negative smear tests (P=0.041). The kappa agreement between the tuberculin and QFG-IT tests was 74.5% with a kappa value of 0.45 (SE0.136). Thirteen of the patients studied were infected with HIV and the tuberculin was positive in 5 of the 12 cases (38.5%) in whom it was performed, with the QFG-IT being positive in 9/13 (69.2%).CONCLUSIONS:
The QFG-IT test may be a useful complimentary tool to the tuberculin test in the diagnosis of tuberculosis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Kit de Reagentes para Diagnóstico
/
Tuberculose
/
Linfócitos T
/
Antígenos de Bactérias
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
Es
Ano de publicação:
2010
Tipo de documento:
Article