[Allergen immunotherapy in Iceland 1977-2006]. / Arangur afnaemismedferdar á Islandi 1977-2006.
Laeknabladid
; 96(7-8): 463-8, 2010.
Article
em Is
| MEDLINE
| ID: mdl-20601746
ABSTRACT
INTRODUCTION:
The prevelance of allery and asthma has increased rapidly over the last 3 decades and is now estimated that 25-30% of population in Western industrialized countries show symptoms of allergy or asthma. The aim of this study was to reveal the success of allergen immunotherapy (AIT) in Landspitali from 1977-2006. MATERIAL ANDMETHODS:
During the study period a total number of 289 individuals underwent immunotherapy in outpatient clinic of allergy and asthma in Landspítali. A total number of 169 individuals were contacted, of whom 128 (76%) accepted to participate in the study. The evaluation was based on medical records, standardized questionnaire and skin-prick tests.RESULTS:
Patients were evaluated on the average of 20 years after finishing treatment. 118 (92%) patients were desensitized to grass pollen, to birch pollen (30%), cat dander (30%) and dust mite (28%). At the time of the study 67% reported to be asymptomatic or with greatly improved allergy symptoms. Males had better response to AIT than women (p=0.04). Participants with positive family history of allergy and/or asthma in first degree relatives also reported better response to AIT (p=0.02). Furthermore, AIT to grass pollen and dust mite seemed to be more effective than AIT to cat dander and birch (p=0.04). AIT was also shown to reduce asthma.CONCLUSION:
AIT for 3-5 years provides significant beneficial effect of allergy and asthma symptoms in patients who undergo such therapy. Finally, it s findings support the notion that AIT may reduce the risk of new allergic manifestations.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Dessensibilização Imunológica
/
Hipersensibilidade
/
Imunoterapia
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
/
Newborn
País como assunto:
Europa
Idioma:
Is
Ano de publicação:
2010
Tipo de documento:
Article