Excited state behaviour of substituted dipyridophenazine Cr(III) complexes in the presence of nucleic acids.
Photochem Photobiol Sci
; 9(9): 1196-202, 2010 Sep 24.
Article
em En
| MEDLINE
| ID: mdl-20617266
ABSTRACT
The photophysics and photochemistry of [Cr(phen)(2)(dppz)](3+) and its 11,12-substituted derivatives [Cr(phen)(2)(X(2)dppz)](3+) {X = Me or F} have been studied in the presence of purine nucleotides or DNA using steady state and time-resolved absorption and luminescence spectroscopy. 5'-Adenosine monophosphate (5'-AMP) shows only a weak interaction with the excited states of each complex. By contrast they are efficiently quenched by 5'-guanosine monophosphate (5'-GMP), consistent with photo-induced electron transfer. Laser flash photolysis spectroscopy in the presence of 5'-GMP suggests that both forward and back electron-transfers are rapid. All complexes also display a strong affinity for DNA and evidence for both static and dynamic quenching mechanisms is provided.
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1
Base de dados:
MEDLINE
Assunto principal:
Fenazinas
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DNA
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Cromo
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Complexos de Coordenação
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article