[Interaction of monoclonal antibodies with horseradish peroxidase]. / Vzaimodeistvie monoklonal'nykh antitel s peroksidazoi khrena.

ABSTRACT

Properties of four types of monoclonal antibodies to horse-radish peroxidase were investigated. The dissociation constants and molecular-weight composition of the immune complexes were determined. The antibodies are shown to be directed to different epitopes on the polypeptide chain. Results of the theoretical prediction of the epitope localisation are presented. The interaction between the antibodies and peroxidase isozymes were studied.