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An investigation on rheumatoid factor of different immunoglobulin classes in hepatitis B virus carriers.
Watanabe, K; Ohkubo, Y; Funahashi, Y; Nishimaki, T; Moritoh, T; Kasukawa, R; Kaise, S; Tomita, T; Matsukawa, A.
Afiliação
  • Watanabe K; Second Department of Internal Medicine, Fukushima Medical College, Japan.
Clin Rheumatol ; 10(1): 31-7, 1991 Mar.
Article em En | MEDLINE | ID: mdl-2065505
Rheumatoid factor (RF) is known to be present very frequently in HB virus carriers. When RF was assayed in 140 asymptomatic carriers by agglutination method, 20.0% were found to be positive, whereas 2.7% in the controls (p less than 0.01). ELISA for detection of RF isotypes showed RF in carriers to be almost IgMRF only. IgMRF showed a tendency to react more readily to human IgG rather than to rabbit IgG. The incidence of IgMRF positivity was higher among anti-HBe antibody-positive carriers than among anti-HBe antibody negative ones, but the difference between the two populations was not significant. However, the incidence of IgMRF positivity in the group showing hepatic dysfunctions was found to be significantly higher than in the group with normal hepatic functions.
Assuntos
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Base de dados: MEDLINE Assunto principal: Fator Reumatoide / Imunoglobulinas / Hepatite B Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 1991 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Fator Reumatoide / Imunoglobulinas / Hepatite B Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 1991 Tipo de documento: Article