No bones about it: insulin modulates skeletal remodeling.
Cell
; 142(2): 198-200, 2010 Jul 23.
Article
em En
| MEDLINE
| ID: mdl-20655463
ABSTRACT
Advancing the hypothesis that bone remodeling is intimately linked to metabolic homeostasis, Fulzele et al. (2010) and Ferron et al. (2010) present evidence that insulin signaling promotes the activation of bone-forming osteoblasts and enhances production of osteocalcin, a secreted mediator of insulin sensitivity, through modulation of bone resorption.
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MEDLINE
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En
Ano de publicação:
2010
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Article