Lifestyle interventions, insulin resistance, and renal artery stiffness in essential hypertension.
Clin Exp Hypertens
; 32(5): 262-9, 2010.
Article
em En
| MEDLINE
| ID: mdl-20662726
ABSTRACT
The study investigates lifestyle and effective anti-hypertensive intervention in overweight-obese patients can influence insulin-resistance (HOMA-IR) and US Renal-Resistive-Index (RRI). After a 1-year interventional program (including a personalized Mediterranean diet, physical activity increase, smoking withdrawal counseling), 156 Essential Hypertension (EH) patients still have abnormal HOMA-IR, significantly higher in comparison to 159 control group patients. Body mass index (BMI) and cholesterol-high-density-lipoprotein improvement are the best predictors of a HOMA-IR decrease; RRI improves in EH according to lifestyle interventions, but no predictor to RRI is identified. Persistence of IR can be tentatively assumed as a steady sign, persistent also after extended lifestyle intervention in EH, further warranting more intensive dietary interventions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artéria Renal
/
Resistência à Insulina
/
Elasticidade
/
Hipertensão
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Estilo de Vida
Tipo de estudo:
Clinical_trials
/
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Humans
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Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article